GATE BT Biochemistry PYQs & Answers — Page 5

Questions 41–50 of 52. Imported answers require independent review unless marked reviewed.

The hexapeptide P has an isoelectric point (pI) of 6.9. Hexapeptide Q is a variant of P that contains valine instead of glutamate at position 3. The two peptides are analyzed by polyacrylamide gel electrophoresis at pH 8.0. Which one of the following statements is CORRECT?

Your answerChoose one option.

P will migrate faster than Q towards the anode

P will migrate faster than Q towards the cathode

Both P and Q will migrate together

Q will migrate faster than P towards the anode

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Which one of the following amino acid residues will destabilize an α-helix when inserted in the middle of the helix?

Your answerChoose one option.

Pro

Val

Ile

Leu

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Which one of the following is INCORRECT about protein structures?

Your answerChoose one option.

A protein fold is stabilized by favorable non-covalent interactions

All parts of a fold can be classified as helices, strands or turns

Two non-covalent atoms cannot be closer than the sum of their van der Waals radii

The peptide bond is nearly planar

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Which one of the following metabolic processes in mammalian cells does NOT occur in the mitochondria?

Your answerChoose one option.

Citric acid cycle

Oxidative phosphorylation

Fatty acid β-oxidation

Glycolysis

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Consider a simple uni-substrate enzyme that follows Michaelis-Menten kinetics. When the enzyme catalyzed reaction was carried out in the presence of 10 nM concentration of an inhibitor, there was no change in the maximal velocity. However, the slope of the Lineweaver-Burk plot increased 3-fold. The dissociation constant for the enzyme-inhibitor complex (in nM) is

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An enzyme catalyzes a reaction by

Your answerChoose one option.

decreasing the energy of the substrate.

decreasing the activation energy of the reaction.

decreasing product stability.

increasing the activation barrier of the reaction.

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Natural proteins are composed primarily of 20 α-amino acids. Which one of the following statements is true for any of these amino acids in a solution of pH 1.5?

Your answerChoose one option.

Only the amino group is ionized.

Only the carboxylic acid group is ionized.

Both amino and carboxylic acid groups are ionized.

Both amino and carboxylic acid groups are neutral.

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If a protein contains four cysteine residues, the number of different ways they can simultaneously form two intra-molecular disulphide bonds is ______.

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An enzymatic reaction exhibits Michaelis-Menten kinetics. For this reaction, on doubling the concentration of enzyme while maintaining [S] >> [E₀],

Your answerChoose one option.

both Kₘ and Vₘₐₓ will remain the same.

Kₘ will remain the same but Vₘₐₓ will increase.

Kₘ will increase but Vₘₐₓ will remain the same.

both Kₘ and Vₘₐₓ will increase.

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Match the proteins in Group I with cellular processes in Group II.

Group I: P. p53; Q. Lysozyme; R. Tubulins; S. Histones

Group II: 1. DNA packaging; 2. Apoptosis; 3. Hydrolysis of polysaccharides; 4. Chromosome segregation

Your answerChoose one option.

P-4, Q-2, R-3, S-1

P-2, Q-3, R-1, S-4

P-4, Q-3, R-1, S-2

P-2, Q-3, R-4, S-1

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GATE BT Biochemistry PYQs

Question 33

Question 37

Question 9

Question 10

Question 53

Question 1

Question 2

Question 14

Question 21

Question 29