GATE BT concept:t-cell PYQs & Answers

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concept:t-cell

Attempt a question, record the concept and assumptions, then check the available answer. Rework mistakes after revising the relevant concepts. Topic tags can overlap; review the question context.

Questions 1–7 of 7. Imported answers require independent review unless marked reviewed.

Topic practice 7 questionsPage 1 of 1

The diversity in T-cell receptors is generated by

Your answerChoose one option.

gene rearrangements

somatic hypermutation of rearranged V region

gene conversion

class switching

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Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II.

Group I	Group II
P. Anergy	1. Elimination of activated T-cells after antigen clearance
Q. Activation-induced cell death	2. Inhibition of auto-reactive T-cells at periphery
R. Receptor editing	3. Unresponsiveness to antigens due to lack of co-stimulatory molecules
S. Regulatory T-cells	4. Elimination of auto-reactive B-cells

Your answerChoose one option.

P-3, Q-1, R-4, S-2

P-4, Q-3, R-1, S-2

P-3, Q-4, R-2, S-1

P-3, Q-2, R-4, S-1

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Match the cell type (Column I) with its function (Column II).

Column I P. B cells Q. Neutrophils R. T cells S. Mast cells

Column II

Humoral immunity

Cytotoxicity

Histamine-associated allergy

Phagocytosis

Your answerChoose one option.

P-1, Q-2, R-3, S-4

P-1, Q-4, R-2, S-3

P-4, Q-3, R-1, S-2

P-4, Q-3, R-2, S-1

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Which of the following statements about immune response are CORRECT? [P] T cells are activated by antigen-presenting cells [Q] Foreign peptides are not presented to helper T cells by Class II MHC proteins [R] Dendritic cells are referred to as professional antigen-presenting cells

Your answerChoose one option.

P and R only

P and Q only

Q and R only

P, Q and R

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Antibody-producing hybridoma cells are generated by the fusion of a

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T cell with a myeloma cell

B cell with a myeloma cell

macrophage with a myeloma cell

T cell and a B cell

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Macrophages eliminate pathogenic bacteria upon activation by

Your answerChoose one option.

NK cells

basophils

CD4+ T cells

plasma cells

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Which of the following conditions promote the development of human autoimmune disorders?

P. Inability to eliminate self-reactive lymphocytes Q. Generation of auto-antibodies R. Ability to eliminate self-reactive T-cells S. Induction of regulatory T-cells in the thymus

Your answerChoose one option.

P, R

Q, S

P, Q

R, S

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GATE BT concept:t-cell PYQs

How to practice concept:t-cell

Question 15

Question 36

Question 38

Question 28

Question 34

Question 13

Question 55