Biotechnology
GATE BT Molecular Biology PYQs
Build your understanding with focused practice from past exam papers.
How to practice Molecular Biology
Attempt a question, record the concept and assumptions, then check the available answer. Rework mistakes after revising the relevant concepts. Topic tags can overlap; review the question context.
Questions 1–10 of 50. Imported answers require independent review unless marked reviewed.
Question 22
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The RNA primer synthesised during bacterial DNA replication is removed by ________.
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Open questionBTMSQ2 marksNeeds review
Messenger RNAs (mRNAs) translate to generate polypeptides and the translation terminates at the UGA, UAG or UAA stop codons. The AGA codon acts as additional stop codon in the mitochondria. The longest possible polypeptide(s) that can be hypothetically translated in the cytosol and/or mitochondria, from the given full length mRNA sequence (36 nucleotides) is/are
5′- AACACUAGACCAUGGCGAGACGUAGUUAAA- 3′
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 43
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The RNA sequence below depicts the part of a 330 nucleotides long mRNA and it encodes the C-terminal portion of a protein.
5′-… … … AAC ACC CGC CCU GUG GCG ACG UAG- 3′
A mutation was identified in this RNA, denoted as 322A→U. This nucleotide change is represented by which of the following class(es) of mutation?
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 48
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Which of the following is/are posttranslational modification(s) involved in epigenetic control of gene expression?
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 16
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Which one of the following is true for piRNAs?
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 22
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Which of the following enzymes is/are involved in the biogenesis of miRNA?
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The contour length of a B-DNA molecule that encodes a bacterial protein of 33 kDa is _____ nm.
Consider the average molecular weight of an amino acid as 110 Da and helix rise per base pair for B-DNA as 0.34 nm.
(Round off to the nearest integer)
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 40
Open questionBTMCQ2 marksNeeds review
Correctly match the Enzyme with its respective Function.
| Enzyme | Function |
| P. Gyrase | 1. Removes a damaged base by cleaving the bond between sugar and base |
| Q. Deadenylase | 2. Provides a swivel allowing one DNA strand to rotate around the other |
| R. Glycosylase | 3. Catalyses bond formation between 3′-OH and 5′-phosphate end of nucleotides in duplex DNA |
| S. DNA ligase | 4. Is an exonuclease that removes the poly(A) tail |
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Which of the following statements about initiation of DNA replication in eukaryotes is/are true?
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Which of the following statements is/are true about telomerase?
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