How to practice topic:computational-tools

Attempt a question, record the concept and assumptions, then check the available answer. Rework mistakes after revising the relevant concepts. Topic tags can overlap; review the question context.

Questions 1–10 of 17. Imported answers require independent review unless marked reviewed.

Topic practice 17 questionsPage 1 of 2

Question 30

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BTMSQ1 markNeeds review
BLAST and its extensions can be used to determine similarity of a query protein sequence with which of the following database(s)?
Your answerSelect all correct options. You can choose more than one.

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Question 47

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BTMCQ2 marksNeeds review
Correctly match the following Bioinformatic tool/Database with its respective Utility.
Bioinformatic tool/Database
Utility
P. BLAST
1. Database for 3D protein structures
Q. Bowtie
2. Tool to identify similarity of a query sequence to existent sequences available in databanks
R. AlphaFold
3. Tool to align short read DNA sequences obtained from Next-generation sequencing to a reference genome
S. PDB
4. AI tool to predict protein structures
Your answerChoose one option.

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Question 26

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BTMCQ1 markNeeds review
Which one of the following programs is used for finding distantly related (or remote) protein homologs?
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Question 27

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Which one of the following is used for global alignment of two protein sequences?
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Question 51

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BTNAT2 marksNeeds review
If there are three unrooted trees for four protein sequences, the number of rooted trees for the same number of sequences is __________.

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Question 24

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Which of the following is NOT used for generating an optimal alignment of two nucleotide sequences?
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Question 44

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BTMCQ2 marksNeeds review
The maximum parsimony method is used to construct a phylogenetic tree for a set of sequences. Which one of the following statements about the method is CORRECT?
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Question 3

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Number of unrooted trees in a phylogeny of five sequences is
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Question 32

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BTMCQ2 marksNeeds review
Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?
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Question 54

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BTNAT2 marksNeeds review
An algorithm was designed to find globins in protein sequence databases. A database which has 78 globin sequences was searched using this algorithm. The algorithm retrieved 72 sequences of which only 65 were globins. The sensitivity of this algorithm is __________ % (round off to 2 decimal places).

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