GATE BT topic:computational-tools PYQs & Answers — Page 2

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topic:computational-tools

Questions 11–17 of 17. Imported answers require independent review unless marked reviewed.

Topic practice 17 questionsPage 2 of 2

Which one of the following is a database of protein sequence motifs?

Your answerChoose one option.

PROSITE

TREMBL

SWISSPROT

PDB

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Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?

P. A larger E-value indicates higher sequence similarity Q. E-value < 10⁻¹⁰ indicates sequence homology R. A higher BLAST score indicates higher sequence similarity S. E-value > 10¹⁰ indicates sequence homology

Your answerChoose one option.

P, Q and R only

Q and R only

P, R and S only

P and S only

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Which of the following components constitute a molecular mechanics force field?

P. Bond stretching Q. Bond angle bending R. Torsional bond rotation S. Non-bonded interactions

Your answerChoose one option.

P and Q only

P, Q and R only

P, Q and S only

P, Q, R and S

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Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?

Your answerChoose one option.

blastp

blastn

blastx

tblastn

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Identify the character based method(s) used for the construction of a phylogenetic tree.

P. Maximum parsimony Q. Neighbor joining R. Maximum likelihood S. Bootstrapping

Your answerChoose one option.

Q only

P and R only

Q and S only

S only

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Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]

Assertion: Ab initio gene finding algorithms that predict protein coding genes in eukaryotic genomes are not completely accurate.

Reason: Eukaryotic splice sites are difficult to predict.

Your answerChoose one option.

Both [a] and [r] are false

[a] is true but [r] is false

Both [a] and [r] are true and [r] is the correct reason for [a]

Both [a] and [r] are true but [r] is not the correct reason for [a]

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Consider the following alignment of two DNA sequences:

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is (up to one decimal place)

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GATE BT topic:computational-tools PYQs

Question 4

Question 29

Question 6

Question 7

Question 18

Question 29

Question 51