Biotechnology
GATE BT topic:immunology PYQs
Build your understanding with focused practice from past exam papers.
How to practice topic:immunology
Attempt a question, record the concept and assumptions, then check the available answer. Rework mistakes after revising the relevant concepts. Topic tags can overlap; review the question context.
Questions 1–10 of 27. Imported answers require independent review unless marked reviewed.
Question 37
Open questionBTMCQ2 marksNeeds review
Match the immunological terms in Column I with their function/description in the Column II
Column I: P. J gene; Q. Cyclosporin; R. Epitope; S. Hapten
Column II: 1. Suppresses immune system by blocking calcineurin; 2. Antibody binding site on a large molecule; 3. Small foreign molecule which elicits an immune response only when combined with a carrier molecule; 4. Contributes to antibody diversity
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 15
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The diversity in T-cell receptors is generated by
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 39
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Correctly match the type of Hypersensitivity reaction with its respective Example.
| Hypersensitivity reaction | Example |
| P. Type I | 1. Tuberculin reaction |
| Q. Type II | 2. Arthus reaction |
| R. Type III | 3. Chronic urticaria |
| S. Type IV | 4. Systemic anaphylaxis |
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 18
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2-mercaptoethanol breaks the ________ covalent bond between light and heavy chain of an immunoglobulin molecule.
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 26
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If a denatured protein of human origin is injected into a rabbit, antibodies generated will recognize the ________ structure of the protein.
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 16
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Which one of the following drugs is NOT an immune checkpoint inhibitor?
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 17
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Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?
P. Basic leucine zipper ATF-like transcription factor 3 (BATF3)
Q. Membrane associated ring-CH-type finger 1 (MARCH-1)
R. Solute carrier family 10 member 1 (SLC10A1)
S. Class II-associated invariant chain peptide (CLIP)
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 18
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Which one of the following is required for the development of B-cells in the bone marrow?
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 36
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Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II.
Group I | Group II |
|---|---|
P. Anergy | 1. Elimination of activated T-cells after antigen clearance |
Q. Activation-induced cell death | 2. Inhibition of auto-reactive T-cells at periphery |
R. Receptor editing | 3. Unresponsiveness to antigens due to lack of co-stimulatory molecules |
S. Regulatory T-cells | 4. Elimination of auto-reactive B-cells |
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You can attempt this question now. Sign in to view the answer key, explanations and discussion.Log in to check answerQuestion 38
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Match the cell type (Column I) with its function (Column II).
Column I
P. B cells
Q. Neutrophils
R. T cells
S. Mast cells
Column II
Humoral immunity
Cytotoxicity
Histamine-associated allergy
Phagocytosis
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