GATE BT topic:molecular-biology PYQs & Answers — Page 2

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topic:molecular-biology

Questions 11–20 of 50. Imported answers require independent review unless marked reviewed.

Topic practice 50 questionsPage 2 of 5

Which of the following methods is/are used for identifying histone modifications?

Your answerSelect all correct options. You can choose more than one.

ChIP-seq

Mass spectrometry

Immunofluorescence

Patch-clamp electrophysiology

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All pseudogenes DO NOT code for a ________.

Your answerChoose one option.

protein with original function

protein with altered function

RNA with coding sequence

RNA with regulatory function

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Match the enzyme (Column I) with its corresponding function (Column II).

Column I Column II P. Primase 1. RNA dependent RNA synthesis Q. Reverse transcriptase 2. DNA dependent DNA synthesis R. RNA Replicase 3. RNA dependent DNA synthesis S. DNA Polymerase III 4. DNA dependent RNA synthesis

Your answerChoose one option.

P-4; Q-1; R-3; S-2

P-2; Q-1; R-3; S-4

P-3; Q-4; R-2; S-1

P-4; Q-3; R-1; S-2

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Match the genetic disorder (Column I) with its molecular basis (Column II).

Column I: P. Sickle-cell anemia Q. Xeroderma pigmentosum R. Tay-Sachs disease S. Down Syndrome

Column II:

Mutation in nucleotide excision repair

Trisomy of chromosome 21

Mutation in β-globin gene

Mutation in hexosaminidase A gene

Your answerChoose one option.

P-1; Q-4; R-2; S-3

P-3; Q-4; R-1; S-2

P-3; Q-1; R-4; S-2

P-4; Q-2; R-3; S-1

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Which of the following statements regarding the below mentioned mRNA sequence is/are TRUE?

5-UGAUGACCUUACCGGAACGAAUUAA-3

Your answerSelect all correct options. You can choose more than one.

It contains nine codons in the reading frame

It contains ten codons in the reading frame

It codes for eight amino acids

It codes for nine amino acids

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Which of the following conditions induce(s) the expression of β-galactosidase gene in the lac operon?

Your answerSelect all correct options. You can choose more than one.

Absence of glucose

Absence of lactose

Presence of glucose

Presence of lactose

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Eukariotic transcription is carried out by

Your answerChoose one option.

DNA-dependent RNA polymerase

DNA-dependent DNA polymerase

RNA-dependent DNA polymerase

RNA-dependent RNA polymerase

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Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].

Assertion [a]: In multicellular organisms, cells of different lineages have different gene expression profiles.

Reason [r]: Alternative splice is the only mechanism to generate protein diversity.

Your answerChoose one option.

Both [a] and [r] are false

Both [a] and [r] are true and [r] is the correct reason for [a]

Both [a] and [r] are true but [r] is not the correct reason for [a]

[a] is true but [r] is false

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Match the types of RNA in Group I with their corresponding function in Group II.

Group I: P. mRNA Q. rRNA R. miRNA S. tRNA

Group II:

Serves as adapters between mRNA and amino acids during protein synthesis

Regulates post-transcriptional gene expression

Codes for proteins

Forms the core of the ribosome structure and catalyses protein synthesis

Your answerChoose one option.

P-3, Q-4, R-2, S-1

P-3, Q-4, R-1, S-2

P-4, Q-3, R-2, S-1

P-2, Q-1, R-4, S-3

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The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)

Your answerSelect all correct options. You can choose more than one.

gene amplification

promoter methylation

loss of heterozygosity

histone acetylation

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GATE BT topic:molecular-biology PYQs

Question 55

Question 27

Question 38

Question 42

Question 50

Question 51

Question 11

Question 13

Question 25

Question 39