GATE BT topic:molecular-biology PYQs & Answers — Page 4

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topic:molecular-biology

Questions 31–40 of 50. Imported answers require independent review unless marked reviewed.

Topic practice 50 questionsPage 4 of 5

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].

Assertion [a]: Dam methylase protects E. coli DNA from phage endonucleases

Reason [r]: E. coli Dam methylase methylates the adenosine residue in the sequence “GATC”

Your answerChoose one option.

Both [a] and [r] are true and [r] is the correct reason for [a]

Both [a] and [r] are true but [r] is not the correct reason for [a]

Both [a] and [r] are false

[a] is false but [r] is true

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The sequence of a 1 Mb long DNA is random. This DNA has all four bases occurring in equal proportion. The number of nucleotides, on average, between two successive EcoRI recognition site GAATTC is ____________.

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E. coli was grown in ¹⁵N medium for several generations. Cells were then transferred to ¹⁴N medium, allowed to grow for 4 generations and DNA was isolated immediately. The proportion of total DNA with intermediate density is __________ (round off to 2 decimal places).

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The amino acid sequence of a peptide is Phe-Ile-Ile-Met-Ser-Leu. The number of codons that encode the amino acids present in this peptide is given below:

Phe: 2 codons

Leu: 6 codons

Ile: 3 codons

Met: 1 codon

Ser: 4 codons

The number of unique DNA sequences that can encode this peptide is __________.

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A mutation in a gene that codes for a polypeptide results in a variant polypeptide that lacks the last three amino acids. What type of mutation is this?

Your answerChoose one option.

Synonymous mutation

Nonsense mutation

Missense mutation

Silent mutation

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Which one of the following covalent linkages exists between 7-Methyl guanosine (m⁷G) and mRNAs?

Your answerChoose one option.

2′–3′ triphosphate

3′–5′ triphosphate

5′–5′ triphosphate

2′–5′ triphosphate

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The molecular mass of a protein is 22 kDa. The size of the cDNA (excluding the untranslated regions) that codes for this protein is ______ kb (rounded off to 1 decimal place).

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The repeat sequence of telomere in humans is

Your answerChoose one option.

5′-TTAAT-3′

5′-TTAGG-3′

5′-GGCCC-3′

5′-AAAAA-3′

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If a segment of a sense strand of DNA is 5′-ATGACAGA-3′, then the resulting RNA sequence after transcription is

Your answerChoose one option.

5′-AGACCAGTA-3′

5′-UCGUCCAU-3′

5′-UACCUGUCU-3′

5′-AUGACAGA-3′

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Match the classes of RNA molecules in Group I with their functions in Group II.

Group I P. snoRNA Q. piRNA R. miRNA S. snRNA

Group II

Protects germline from transposable elements

Blocks translation of selected mRNA

Template for telomere elongation

Modification and processing of rRNA

Splicing of RNA transcripts

Your answerChoose one option.

P-3, Q-5, R-2, S-4

P-1, Q-3, R-2, S-5

P-1, Q-4, R-5, S-2

P-4, Q-1, R-2, S-5

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GATE BT topic:molecular-biology PYQs

Question 35

Question 43

Question 44

Question 47

Question 11

Question 36

Question 48

Question 3

Question 4

Question 28