GATE XL concept:genetic-disorders PYQs & Answers

Questions 1–3 of 3. Imported answers require independent review unless marked reviewed.

Which of the following genetic disorders is/are caused by trinucleotide repeat expansions?

Your answerSelect all correct options. You can choose more than one.

Huntington’s disease

β-thalassemia

Fragile X syndrome

Cystic fibrosis

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Match the syndromes listed in Column I with the cause/symptoms listed in Column II

Column I: P. Prader-Willi syndrome; Q. Down syndrome; R. Cushing syndrome; S. Turner syndrome; T. Fanconi syndrome

Column II: (i) a collection of signs and symptoms due to prolonged exposure to corticosteroids like cortisol; (ii) a syndrome of inadequate reabsorption in the proximal renal tubule of the kidney; (iii) a genetic disorder usually caused by the deletion of a part of chromosome 15; (iv) a genetic disorder caused by the presence of all or part of a third copy of chromosome 21; (v) a genetic condition in which a female has partially or completely missing an X chromosome

Your answerChoose one option.

P – (ii) ; Q – (v) ; R – (iv) ; S – (iii) ; T – (i)

P – (iv) ; Q – (ii) ; R – (i) ; S – (iii) ; T – (v)

P – (iii) ; Q – (iv) ; R – (i) ; S – (v) ; T – (ii)

P – (v) ; Q – (iv) ; R – (ii) ; S – (i) ; T – (iii)

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Match the following genetic disorders in Column I with associated typical chromosomal changes mentioned in Column II

Column I P. Klinefelter syndrome Q. Down syndrome R. Turner syndrome S. Cri du chat syndrome

Column II (i) 45,XO (ii) 5p minus (iii) 47,XXY (iv) Trisomy 21

Your answerChoose one option.

P-(iv), Q-(ii), R-(ii), S-(i)

P-(iv), Q-(ii), R-(i), S-(ii)

P-(ii), Q-(iv), R-(ii), S-(i)

P-(iii), Q-(iv), R-(i), S-(ii)

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GATE XL concept:genetic-disorders PYQs

How to practice concept:genetic-disorders

Question 101

Question 95

Question 13