GATE XL discipline:life-sciences PYQs & Answers — Page 28

Questions 271–280 of 1235. Imported answers require independent review unless marked reviewed.

Given the standard reduction potentials (E⊖) for the half-cell reactions below, the standard Gibbs free energy of the dissolution of silver chloride in water, at 298 K, is __________ J mol⁻¹ (rounded off to nearest integer).

(Given: Faraday constant, F = 96500 C mol⁻¹; J = C × V)

AgCl(s) + e⁻ → Ag(s) + Cl⁻(aq) ; E⊖ = 0.22 V at 298 K

Ag⁺(aq) + e⁻ → Ag(s) ; E⊖ = 0.80 V at 298 K

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Which one of the following pairs of amino acids is NOT incorporated in a polypeptide chain?

Your answerChoose one option.

4-Hydroxyproline and γ-carboxyglutamate

γ-Carboxyglutamate and desmosine

Ornithine and citrulline

4-Hydroxyproline and 5-hydroxylysine

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Mammalian cells cultured at low temperature (25 to 30 °C) leads to an increased sterol content in the membrane. Elevated sterols in the membrane results in

Your answerChoose one option.

an enhancement in membrane fluidity.

stabilization of membrane proteins.

an increase in membrane permeability to water.

a decrease in membrane fluidity.

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Which one of the following metabolic intermediates is common to glycolysis, nucleotide synthesis and glycogen synthesis?

Your answerChoose one option.

Citrate

Oxaloacetate

Glucose 6-phosphate

Glycerol 3-phosphate

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In mammals, hematopoietic stem cells that give rise to different types of blood cells are known as

Your answerChoose one option.

totipotent stem cells.

pluripotent stem cells.

myeloid progenitor cells.

lymphoid progenitor cells.

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Which one or more of the following statements correctly describe(s) the addition of N-nucleotides during the rearrangement of the immunoglobulin heavy chain-encoding gene?

Your answerSelect all correct options. You can choose more than one.

Addition of N-nucleotides is template encoded.

N-nucleotides are added by terminal deoxynucleotidyl transferase.

The added N-nucleotides are common in V-D and D-J junction.

N-nucleotides are added by the DNA polymerase II.

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A newly identified viral protein contains one long α-helix spanning 60 amino acid residues. The number of main chain H-bonds formed in this helix is _________. (Answer in integer)

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In a lactic acid solution at pH 4.8, the concentrations of lactic acid and lactate are 0.01 M and 0.087 M, respectively. The calculated pKa of lactic acid is ________. (Round off to one decimal place)

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If a 10 mM solution of a biomolecule in a cuvette of path length 10 mm absorbs 90% of the incident light at 280 nm, the molar extinction coefficient of the biomolecule at this wavelength is __________ M⁻¹cm⁻¹. (Round off to two decimal places)

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Metabolic intermediates provide the backbone for the synthesis of amino acids. Match the metabolic intermediates listed in Column I with their corresponding amino acids given in Column II.

Column I	Column II
P. α-Ketoglutarate	i. Histidine
Q. Ribose 5-phosphate	ii. Glutamate
R. 3-Phosphoglycerate	iii. Aspartate
S. Phosphoenolpyruvate	iv. Phenylalanine
	v. Serine

Your answerChoose one option.

P-ii; Q-i; R-v; S-iv

P-iii; Q-ii; R-i; S-v

P-iv; Q-iii; R-ii; S-v

P-ii; Q-i; R-iv; S-v

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GATE XL discipline:life-sciences PYQs

Question 27

Question 28

Question 29

Question 30

Question 31

Question 32

Question 33

Question 34

Question 35

Question 36