GATE XL topic:biochemistry-molecular-biology PYQs & Answers — Page 2

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topic:biochemistry-molecular-biology

Questions 11–20 of 33. Imported answers require independent review unless marked reviewed.

Topic practice 33 questionsPage 2 of 4

The organisms that obtain energy from inorganic compounds are known as

Your answerChoose one option.

Autotrophs

Organotrophs

Lithotrophs

Phototrophs

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Match the standard/stated cofactors in Column I with their respective enzymes in Column II

Column I P. Cu²⁺ Q. Se R. Ni²⁺ S. K⁺ T. Mo

Column II (i) Dinitrogenase (ii) Cytochrome oxidase (iii) Pyruvate kinase (iv) Glutathione peroxidase (v) Urease

Your answerChoose one option.

P – (v) ; Q – (ii) ; R – (iv) ; S – (i) ; T – (iii)

P – (ii) ; Q – (iv) ; R – (v) ; S – (iii) ; T – (i)

P – (iv) ; Q – (ii) ; R – (iii) ; S – (i) ; T – (v)

P – (ii) ; Q – (i) ; R – (iii) ; S – (iv) ; T – (v)

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Which of the following techniques is/are used for determining the three-dimensional structure of proteins?

Your answerSelect all correct options. You can choose more than one.

Cryo-electron Microscopy

Circular Dichroism

Nuclear Magnetic Resonance Spectroscopy

X-ray Diffraction

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Which one of the following organic compounds is composed of only (i) a nitrogen containing base, (ii) a single five-carbon sugar, and (iii) a triphosphate?

Your answerChoose one option.

Nucleoside

Nucleotide

Base

Nucleic acid

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The action of which class of enzyme inhibitors can be reversed by adding an excess of substrate?

Your answerChoose one option.

Uncompetitive inhibitors

Competitive inhibitors

Non-specific inhibitors

Allosteric inhibitors

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2-Deoxyglucose (2-DG) inhibits the proliferation of cells and hence finds use as an anti-cancer agent. It is also used in COVID therapy, where it blocks hyperproliferation of virus-infected cells. Mechanically, 2-DG blocks glycolysis by inhibiting the activities of which of the following enzyme/s?

Your answerSelect all correct options. You can choose more than one.

Hexokinase

Glucose 6-phosphate isomerase

Glucose-6 phosphate dehydrogenase

Phosphofructokinase

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Assume that the anticodon for an unknown amino acid is 3′ AUG 5′. The corresponding code on DNA sequence would be

Your answerChoose one option.

3′ TAC 5′

5′ TAG 3′

3′ ATG 5′

5′ ATG 3′

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In the structure of a polypeptide, one α-helix (3.6₃ helix) contains 32 intra-chain hydrogen bonds. The number of turns in the helix will be ________ (in integer).

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Match the therapeutic factors in Column I with the applications in Column II

Column I P. Humulin Q. Erythropoietin R. Plasminogen activator S. Cathepsin K inhibitor T. Leptin

Column II (i) Cancer therapy (ii) Diabetes (iii) Osteoporosis (iv) Anaemia (v) Myocardial infarction (vi) Obesity

Your answerChoose one option.

P-(ii), Q-(iv), R-(v), S-(iii), T-(vi)

P-(ii), Q-(v), R-(i), S-(iv), T-(iii)

P-(v), Q-(vi), R-(iv), S-(iii), T-(i)

P-(iii), Q-(iv), R-(ii), S-(v), T-(vi)

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Which of the following amino acids contain more than one chiral center?

Your answerSelect all correct options. You can choose more than one.

Leucine

Isoleucine

Serine

Threonine

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GATE XL topic:biochemistry-molecular-biology PYQs

Question 89

Question 97

Question 99

Question 85

Question 88

Question 98

Question 4

Question 10

Question 14

Question 18