GATE XL topic:biological-sciences PYQs & Answers — Page 41

Questions 401–410 of 1235. Imported answers require independent review unless marked reviewed.

DNA in a 1 cm long chromatin contains 5 × 10⁹ base pairs. The fold compaction of this DNA within the chromatin is ______ (in integer).

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Intracellular concentrations of ATP, ADP, and inorganic phosphate in four cell types are given below. Which one of these cell types has the most negative

for ATP hydrolysis?

Cell type	ATP (mM)	ADP (mM)	Inorganic phosphate (mM)
L	3.0	1.8	5.0
K	3.9	1.3	3.0
B	2.7	0.7	2.7
M	7.2	0.9	8.0

Your answerChoose one option.

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Which one of the following amino acids has more than two acid-base groups?

Your answerChoose one option.

Alanine

Leucine

Phenylalanine

Tyrosine

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Enzyme activity profiles as a function of time in the absence or presence of different types of feedback mechanisms are shown in the figure below. Match the following feedback mechanisms with the corresponding profiles in the figure. (p) No feedback mechanism (q) Negative feedback mechanism with short delay (r) Negative feedback mechanism with long delay (s) Positive feedback mechanism

Your answerChoose one option.

(p) – (i); (q) – (ii); (r) – (iii); (s) – (iv)

(p) – (iv); (q) – (iii); (r) – (ii); (s) – (i)

(p) – (iv); (q) – (ii); (r) – (iii); (s) – (i)

(p) – (i); (q) – (iii); (r) – (ii); (s) – (iv)

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A linear DNA fragment of 5 kilobase (kb) when completely digested with EcoRI produces 2.5 kb, 1.5 kb, and 1 kb fragments. Complete digestion of the same 5 kb fragment with XbaI produces 3.5 kb and 1.5 kb fragments. Which one of the following sets of fragments will be obtained if the 5 kb fragment is fully digested with EcoRI and XbaI simultaneously?

Your answerChoose one option.

3 kb and 2 kb

2 kb and 1 kb

2 kb, 1.5 kb, 1 kb, and 0.5 kb

2.5 kb, 1.5 kb, 0.75 kb, and 0.25 kb

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Match the cell types listed in Group I with associated processes listed in Group II. Group I (p) NK cells (q) B cells (r) Mast cells (s) Neutrophils

Group II (i) Antibody production (ii) First cells to be recruited at the site of infection (iii) Antibody-dependent cell-mediated cytotoxicity (iv) Histamine production

Your answerChoose one option.

(p) – (ii); (q) – (i); (r) – (iii); (s) – (iv)

(p) – (ii); (q) – (i); (r) – (iv); (s) – (ii)

(p) – (iii); (q) – (i); (r) – (iv); (s) – (ii)

(p) – (iii); (q) – (ii); (r) – (i); (s) – (iv)

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Four statements about lipids are given below as options. Choose the statement(s) which is/are CORRECT.

Your answerSelect all correct options. You can choose more than one.

Cholesterol is amphipathic

Self-assembly of phospholipids in water is due to hydrophobic effect

The temperature at which the gel phase changes to liquid crystal phase increases with an increase in the degree of unsaturation of fatty acyl tails

The choline head group of lipids is positively charged

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Which of the following technique(s) can be used to separate proteins according to their molecular weights from a mixture of proteins?

Your answerSelect all correct options. You can choose more than one.

Ion exchange chromatography

Size exclusion chromatography

Sodium dodecylsulfate – polyacrylamide gel electrophoresis (SDS-PAGE)

Sucrose density gradient centrifugation

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B cells produce two forms of an immunoglobulin: (i) membrane-bound form, known as B cell receptor (BCR) and (ii) soluble form, known as antibody. Which of the following statements is/are CORRECT about BCR and antibody produced by the same B cell?

Your answerSelect all correct options. You can choose more than one.

BCR and antibody have identical antigen binding site

BCR and antibody recognize different epitopes

BCR and antibody are encoded by the same gene

BCR and antibody are formed by differential splice

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A 100 ml solution of pH 10 was well-mixed with a 100 ml solution of pH 4. The pH of the resultant 200 ml solution is __________ (rounded off to two decimal places).

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GATE XL topic:biological-sciences PYQs

Question 35

Question 36

Question 37

Question 38

Question 39

Question 40

Question 41

Question 42

Question 43

Question 44