GATE XL year:2023 PYQs & Answers — Page 4

Questions 31–40 of 122. Imported answers require independent review unless marked reviewed.

Given below are four reactions of the glycolytic pathway catalyzed by the enzymes E1, E2, E3 and E4, as indicated.

(i) Fructose 6-phosphate

Fructose 1,6-bisphosphate

(ii) Fructose 1,6-bisphosphate

Dihydroxyacetone phosphate + Glyceraldehyde 3-phosphate

(iii) 3-Phosphoglycerate

2-Phosphoglycerate

(iv) Phosphoenolpyruvate

Pyruvate

Which of these enzymes is/are NOT part of the gluconeogenesis pathway?

Your answerSelect all correct options. You can choose more than one.

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Which of the following molecules is/are second messenger(s) produced by the phosphoinositide signaling cascade?

Your answerSelect all correct options. You can choose more than one.

Phosphatidylinositol 4,5-bisphosphate

Inositol 1,4,5-triphosphate

Inositol 1,3,5-triphosphate

Diacylglycerol

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A protein has seven cysteine residues. The maximum number of disulfide bonds of different combinations that can possibly be formed by these seven cysteine residues is ______ (in integer).

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A lyophilized sample of 20 nanomoles of an oligonucleotide is dissolved in water and the volume of the solution is made up to 200 μL. The concentration (in μM) of the oligonucleotide in this solution is ______ (in integer).

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DNA in a 1 cm long chromatin contains 5 × 10⁹ base pairs. The fold compaction of this DNA within the chromatin is ______ (in integer).

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Intracellular concentrations of ATP, ADP, and inorganic phosphate in four cell types are given below. Which one of these cell types has the most negative

for ATP hydrolysis?

Cell type	ATP (mM)	ADP (mM)	Inorganic phosphate (mM)
L	3.0	1.8	5.0
K	3.9	1.3	3.0
B	2.7	0.7	2.7
M	7.2	0.9	8.0

Your answerChoose one option.

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Which one of the following amino acids has more than two acid-base groups?

Your answerChoose one option.

Alanine

Leucine

Phenylalanine

Tyrosine

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Enzyme activity profiles as a function of time in the absence or presence of different types of feedback mechanisms are shown in the figure below. Match the following feedback mechanisms with the corresponding profiles in the figure. (p) No feedback mechanism (q) Negative feedback mechanism with short delay (r) Negative feedback mechanism with long delay (s) Positive feedback mechanism

Your answerChoose one option.

(p) – (i); (q) – (ii); (r) – (iii); (s) – (iv)

(p) – (iv); (q) – (iii); (r) – (ii); (s) – (i)

(p) – (iv); (q) – (ii); (r) – (iii); (s) – (i)

(p) – (i); (q) – (iii); (r) – (ii); (s) – (iv)

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A linear DNA fragment of 5 kilobase (kb) when completely digested with EcoRI produces 2.5 kb, 1.5 kb, and 1 kb fragments. Complete digestion of the same 5 kb fragment with XbaI produces 3.5 kb and 1.5 kb fragments. Which one of the following sets of fragments will be obtained if the 5 kb fragment is fully digested with EcoRI and XbaI simultaneously?

Your answerChoose one option.

3 kb and 2 kb

2 kb and 1 kb

2 kb, 1.5 kb, 1 kb, and 0.5 kb

2.5 kb, 1.5 kb, 0.75 kb, and 0.25 kb

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Match the cell types listed in Group I with associated processes listed in Group II. Group I (p) NK cells (q) B cells (r) Mast cells (s) Neutrophils

Group II (i) Antibody production (ii) First cells to be recruited at the site of infection (iii) Antibody-dependent cell-mediated cytotoxicity (iv) Histamine production

Your answerChoose one option.

(p) – (ii); (q) – (i); (r) – (iii); (s) – (iv)

(p) – (ii); (q) – (i); (r) – (iv); (s) – (ii)

(p) – (iii); (q) – (i); (r) – (iv); (s) – (ii)

(p) – (iii); (q) – (ii); (r) – (i); (s) – (iv)

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GATE XL year:2023 PYQs

Question 31

Question 32

Question 33

Question 34

Question 35

Question 36

Question 37

Question 38

Question 39

Question 40